Another ding {{ FIRSTNAME | there }}? Researchers have developed a new material that can repair itself up to 1'000 times. They plan to use it for aeroplanes, in space, and, of course, to have your car self-heal like a Transformer.
Send this to your friend who's always crashing into stuff. 💥🚗
In This Open Letter
MedTech: SA startup turns fame into R85M raise.
Local: Eskom's Bitcoin plan & new SA gold coins.
Global: Google turns Gemini into your AI intern.
Tech Jobs: 6 new data & dev roles up for grabs.
Beyond: The No.1 early-stage founder lesson.
Work Smarter: How to get VC funding in SA.
Final call: Startup of the Year entries close Monday! 🚀
Innovation City's Startup of the Year 2026 is closing entries on 27 April. Pitch to investors and ecosystem enablers, win a year of Innovation City membership and Founder Collab access. Don't miss your shot.
TRENDING NOW
This SA Startup of the Year Alum Just Raised R85m to Fight TB With AI
TB is still the world's leading infectious disease, killing 1.23 million people globally, 54'000 of them in South Africa (one of the 30 highest-burden countries) in 2024 alone – this local venture is using their early Startup of the Year traction to change the game from SA…
We first covered AI Diagnostics in July 2024, the same year they took home the Innovation City Startup of the Year title, getting instant national recognition and access to investors and ecosystem enablers.
What that fame enabled them to do, though, is the real story…
The product, in case you missed it
AI Diagnostics makes an AI-powered digital stethoscope called the Ostium. A nurse holds it to a patient's chest, the device captures lung sounds, and the AI flags whether those sounds carry patterns associated with TB. No x-ray, radiologist – you don’t even need a specialist in the room.
Co-founder and CEO Braden van Breda came up through MedTech, building products for cardiothoracic specialists before realising Sub-Saharan Africa doesn't have nearly enough of them to deliver the interventions being designed. The most abundant healthcare resource we have here isn't specialists. It's nurses and community health workers. So he built for them.

‘Cos when it works, it just works…
From one pilot to 10+ countries
When we featured them, they'd just completed their first pilot in the Western Cape. Since then: A commercial launch in South Africa, clinical programmes running across more than 10 countries (including Zambia, Nigeria, Ghana, Kenya, India, Pakistan, Vietnam and Thailand), and a nine-country validation study underway with Stop TB, a technical partner of the WHO.
The goal? A WHO endorsement, which unlocks access to the Global Fund's procurement list, the mechanism through which most of the world's TB programmes are actually funded. And rather than waiting to see if the endorsement lands, the team is already building the distribution infrastructure, clinical support systems and firmware update capabilities needed to operate at that scale. As Braden puts it: plan for success.
This month, AI Diagnostics closed a pre-Series A raise of R85 million, led by The Steele Foundation for Hope with participation from the iFSP Group, Global Innovation Fund and follow-on from key angel investors. But Braden specifically points out that a big part of AI Diagnostics' success is the team behind it: 16 permanent staff, plus an extended network of development and research partners.
When your mission is accessible diagnostics for those who need it most, it turns out, people really want to help you build it.
We're watching this space…
Early recognition helped them gain massive traction. Want the same for your startup? We teamed up with Innovation City for this year's Startup of the Year. Entries close 27 April: Enter now →
Have your say…
CHECK THIS OUT

Meet the team behind some of SA's fastest-growing newsletters
The Newsletter Company is a South African B2B newsletter agency built by the same team behind The Open Letter — the country's leading startup and tech newsletter, reaching 32'000+ professionals daily.
We've taken what we learned building this newsletter you’re reading and turned it into a done-for-you service for B2B scale-ups. The model is simple: We help define your editorial strategy, produce the content, manage the platform, grow the list and optimise performance.
That’s right, we help you grow it: Most agencies can only produce it, but with our commercial experience, we know how to find and engage your dream customer.
Your team's involvement? Approve the copy, check the test send, and watch it compound.
For B2B scale-ups with product-market fit looking to build a real distribution asset, this is how you start owning your audience instead of renting it.
IN SHORT
Easing you into the weekend…
⛏️ Eskom Goes Mining. Remember when we told you Eskom's going Bitcoin mining? The latest is that they need NERSA's approval, and thus need to present them with a framework of how they plan to sell the daytime electricity surplus. Hmmmm.
🦸 Fighting The Bad Guys. Digital banking fraud is on the rise, with nearly 98'000 cases reported last year and nearly R1.9 billion in losses, with AI breaking the old detection rulebook. Here’s what’s happening and who’s fighting back.
🪙 Coining It. SA is getting new gold and silver coins over the next few years. The coins, including a series on the Big 5, The Odyssey, African Range, the Chinese Lunisolar Calendar and the Colours of Africa, will range from R5 to R1'000 and be legal tender like Krugerrands.
🤖 Google's AI Intern. Google has launched a swathe of AI-powered features to Workspace, including building and filling out Google Sheets, new AI writing tools and converting rando data into structured tables. "Hey Gemini, you missed a zero in column B, and I've lost a multi-million Rand deal." "You're absolutely right…"
⏱️ Payroll 8× Faster. Cape Union Mart's payroll team was stuck fixing errors and fighting downtime. So Deel Local Payroll, powered by PaySpace, replaced the old system with a cloud platform that cut payroll processing from 4 days to just half a day, eliminating downtime and freeing the team to focus on real operational improvements.*
* From our partners. Find all the best service providers for your business in our Founder Stack.
Get the best in SA tech and business news →
WORK SMARTER

Should you try to raise funding or…
How to know if you’re a fit for VCs in SA
So many founders try to follow the Silicon Valley model, but the truth is that Africa and South Africa are a different ecosystem, and raising capital could be more trouble than it’s worth (or you might not even need it). So we got the co-founder of one of SA’s best-known venture capital firms to come and show us how they operate…
And it turns out, there are 3 specific steps you can do right now to know if you should go after VC funding or bootstrap in SA.
☝ Send this to a friend who always has 10 new million-dollar ideas.
WHAT YOU SAID
Build it and they won't come…
Yesterday, we showed you Lekker Build’s 60-second website builder, asking about your business website. And would you believe most here haven’t gotten around to it yet…?
🟨🟨🟨🟨⬜️⬜️ 🟢 Yes, and it does real work for me (24%)
🟨🟨🟨🟨🟨⬜️ 🟡 Yes, but it's basically a digital business card (27%)
🟨⬜️⬜️⬜️⬜️⬜️ 🔧 Sort of — just a Facebook page or Google listing (6%)
🟩🟩🟩🟩🟩🟩 🚧 No, but I've been meaning to sort it (30%)
🟨🟨⬜️⬜️⬜️⬜️ ❌ No, and I don't think I need one (13%)
READY FOR A MOVE?
Jobs in Tech
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The name in SA tech employment for over a decade, OfferZen needs no introduction, and their ability to get you placed is only as legendary as the time, energy and money they save employers in finding top skills.
BEYOND THE NEWSLETTER
The No. 1 early-stage founder lesson
We asked a major SA telecoms founder what one piece of advice he'd give to new founders — and what he said is a reminder to stay humbly excited about the road ahead…
Don’t miss all the extra operator interviews and insights content we do on our social channels — come enjoy the vibez.
AROUND THE WEB
Have some fun…
🎵 Tool to Try: GigTrip lets you discover concerts on a map.
📉 That's Interesting: US student math and reading scores have dropped so sharply they've erased nearly two decades of progress, with 13-year-old maths back to 1990s levels. Wonder what our local stats say…
🫧 Next Level: A free diver captured the moment two bubble rings collided and dissolved into one larger circle.
🐼 Wow Site: BlackAndWhiteBear lets you search and view giant pandas.




